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1

Schizophrenia: from phenomenology to neurobiology

Albert Hung Choy Wong, Hubert H.M. Van Tol

Journal:

Neuroscience & Biobehavioral Reviews

Year:

2003

Language:

english

File:

PDF, 511 KB

english, 2003

2

Modulation of Intracellular Cyclic AMP Levels by Different Human Dopamine D4 Receptor Variants

Vida Asghari, Suparna Sanyal, Saskia Buchwaldt, Andrew Paterson, Vera Jovanovic, Hubert H. M. Van Tol

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 904 KB

english, 1995

3

Characterization of a novel D2-like dopamine receptor with a truncated splice variant and a D1-like dopamine receptor unique to invertebrates from Caenorhabditis elegans

Mai Sugiura, Satoshi Fuke, Satoshi Suo, Noboru Sasagawa, Hubert H. M. Van Tol, Shoichi Ishiura

Journal:

Journal of Neurochemistry

Year:

2005

Language:

english

File:

PDF, 1.18 MB

english, 2005

4

Molecular biology of the dopamine receptors

Olivier Civelli, James R. Bunzow, David K. Grandy, Qun-Yong Zhou, Hubert H.M. Van Tol

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1991

Language:

english

File:

PDF, 1.55 MB

english, 1991

5

The dopamine D4 receptor: one decade of research

James N Oak, John Oldenhof, Hubert H.M Van Tol

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 486 KB

english, 2000

6

Binding of 5H-Dibenzo[b,e][1,4]diazepine and Chiral 5H-Dibenzo[a,d]cycloheptene Analogs of Clozapine to Dopamine and Serotonin Receptors

Phillips, Shawn T., de Paulis, Tomas, Baron, Bruce M., Siegel, Barry W., Seeman, Philip, Van Tol, Hubert H. M., Guan, Hong-chang, Smith, Howard E.

Journal:

Journal of Medicinal Chemistry

Year:

1994

Language:

english

File:

PDF, 1.37 MB

english, 1994

7

Dopamine D4 receptor variant in Africans, D4Valine194Glycine, is insensitive to dopamine and clozapine: Report of a homozygous individual

Liu, Ivy S. C., Seeman, Philip, Sanyal, Suparna, Ulpian, Carla, Rodgers-Johnson, Pamela E. B., Serjeant, Graham R., Van Tol, Hubert H. M.

Journal:

American Journal of Medical Genetics

Year:

1996

File:

PDF, 602 KB

1996

8

Dopamine D2-like sites in schizophrenia, but not in Alzheimer's, Huntington's, or control brains, for [3H]benzquinoline

Philip Seeman, Hong-Chang Guan, José Nobrega, Dilshad Jiwa, Rudolph Markstein, Ja-Hyun Balk, Roberto Picetti, Emiliana Borrelli, Hubert H.M. Van Tol

Journal:

Year:

1997

Language:

english

File:

PDF, 218 KB

english, 1997

9

Alleles at the dopamine D4 receptor locus do not contribute to the genetic susceptibility to schizophrenia in a large Swedish kindred

Cathy L. Barr, James L. Kennedy, Jay B. Lichter, Hubert H. M. Van Tol, Lennart Wetterberg, Ken J. Livak, Kenneth K. Kidd

Journal:

American Journal of Medical Genetics Part A

Year:

1993

Language:

english

File:

PDF, 436 KB

english, 1993

10

Dopamine D4 receptor variant, D4GLYCINE194, in Africans, but not in Caucasians: No association with Schizophrenia

Philip Seeman, Carla Ulpian, Guy Chouinard, Hubert H. M. Van Tol, Hy Dwosh, Jeffrey A. Lieberman, Katherine Siminovitch, Ivy S. C. Liu, John Waye, P. Voruganti, Craig Hudson, Graham R. Serjeant, Arni

Journal:

American Journal of Medical Genetics Part A

Year:

1994

Language:

english

File:

PDF, 929 KB

english, 1994

11

Association study between the dopamine D4 receptor gene and schizophrenia

Arturas Petronis, Fabio Macciardi, Andrew Athanassiades, Andrew D. Paterson, Massimiliano Verga, Herbert Y. Meltzer, Philip Cola, Janet A. Buchanan, Hubert H. M. Van Tol, James L. Kennedy

Journal:

American Journal of Medical Genetics Part A

Year:

1995

Language:

english

File:

PDF, 393 KB

english, 1995

12

Microarray analysis of the developing cortex

Mawahib O. Semeralul, Paul C. Boutros, Olga Likhodi, Allan B. Okey, Hubert H.M. Van Tol, Albert H.C. Wong

Journal:

Developmental Neurobiology

Year:

2006

Language:

english

File:

PDF, 667 KB

english, 2006

13

Dopamine D4-Like Receptor Elevation in Schizophrenia: Cloned D2 and D4 Receptors Cannot Be Discriminated by Raclopride Competition Against [3H]Nemonapride

Philip Seeman, Hubert H. M. Van Tol

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 317 KB

english, 1995

14

Low density of dopamine D4 receptors in Parkinson's, schizophrenia, and control brain striata

Philip Seeman, Hong-Chang Guan, Hubert H. M. Van Tol, Hyman B. Niznik

Journal:

Year:

1993

Language:

english

File:

PDF, 863 KB

english, 1993

15

Tryptophan hydroxylase 2 gene expression and promoter polymorphisms in bipolar disorder and schizophrenia

Vincenzo De Luca, Olga Likhodi, Hubert H. M. Van Tol, James L. Kennedy, Albert H. C. Wong

Journal:

Psychopharmacology

Year:

2005

Language:

english

File:

PDF, 115 KB

english, 2005

16

Short- and long-term heterologous sensitization of adenylate cyclase by D4 dopamine receptors

Val J. Watts, Minh N. Vu, Brenda L. Wiens, Vera Jovanovic, Hubert H. M. Van Tol, Kim A. Neve

Journal:

Psychopharmacology

Year:

1999

Language:

english

File:

PDF, 175 KB

english, 1999

17

Regulation of the Rat Oxytocin Gene by Estradiol : Examination of Promoter Activity in Transfected Cells and of Messenger Ribonucleic Acid and Peptide Levels in the Hypothalamo-Neurohypophyseal System

J. Peter, H. Burbach, Roger A. H. Adan, Hubert H. M. van Tol, Marleen A. E. Verbeeck, John F. Axelson, Fred W. van Leeuwen, Johanna M. Beekman, Geert Ab

Journal:

Journal of Neuroendocrinology

Year:

1990

Language:

english

File:

PDF, 1.44 MB

english, 1990

18

Quantitation of Vasopressin mRNA and Oxytocin mRNA in Hypothalamic Nuclei by Solution Hybridization Assays

J. Peter H. Burbach, Hubert H. M. Van Tol, Marleen H. C. Bakkus, Hartwig Schmale, Richard Ivell

Journal:

Journal of Neurochemistry

Year:

1986

Language:

english

File:

PDF, 944 KB

english, 1986

19

D2-class dopamine receptor inhibition of NMDA currents in prefrontal cortical neurons is platelet-derived growth factor receptor-dependent

Michael A. Beazely, Andrew Tong, Wen-Li Wei, Hubert Van Tol, Bikram Sidhu, John F. MacDonald

Journal:

Journal of Neurochemistry

Year:

2006

Language:

english

File:

PDF, 643 KB

english, 2006

20

Cloning and expression of a rat D2 dopamine receptor cDNA

Bunzow, James R., Tol, Hubert H. M. Van, Grandy, David K., Albert, Paul, Salon, John, Christie, MacDonald, Machida, Curtis A., Neve, Kim A., Civelli, Olivier

Journal:

Year:

1988

File:

PDF, 592 KB

1988

21

Cloning and expression of human and rat Dt dopamine receptors

Zhou, Qun-Yong, Grandy, David K., Thambi, Lisa, Kushner, Jake A., Tol, Hubert H. M. Van, Cone, Roger, Pribnow, David, Salon, John, Bunzow, James R., Civelli, Olivier

Journal:

Year:

1990

File:

PDF, 1.03 MB

1990

22

Cloning of the gene for a human dopamine D4 receptor with high affinity for the antipsychotic clozapine

Van Tol, Hubert H. M., Bunzow, James R., Guan, Hong-Chang, Sunahara, Roger K., Seeman, Philip, Niznik, Hyman B., Civelli, Olivier

Journal:

Year:

1991

File:

PDF, 598 KB

1991

23

Cloning of the gene for a human dopamine D5 receptor with higher affinity for dopamine than D1

Sunahara, Roger K., Guan, Hong-Chang, O'Dowd, Brian F., Seeman, Philip, Laurier, Lisanne G., Ng, Gordon, George, Susan R., Torchia, Joeseph, Van Tol, Hubert H. M., Niznik, Hyman B.

Journal:

Year:

1991

File:

PDF, 912 KB

1991

24

Multiple dopamine D4 receptor variants in the human population

Tol, Hubert H. M. Van, Wu, Caren M., Guan, Hong-Chang, Ohara, Koichi, Bunzow, James R., Civelli, Olivier, Kennedy, James, Seeman, Philip, Niznik, Hyman B., Jovanovic, Vera

Journal:

Year:

1992

File:

PDF, 465 KB

1992

25

Echoes of D4 receptor repeats

Lichter, Jay B., Livak, Kenneth J., Rogers, Jeffery, Kennedy, James L., Van Tol, Hubert H. M.

Journal:

Year:

1992

File:

PDF, 139 KB

1992

26

Dopamine D4 receptors elevated in schizophrenia

Seeman, Philip, Guan, Hong-Chang, Van Tol, Hubert H. M.

Journal:

Year:

1993

File:

PDF, 781 KB

1993

27

Dopamine counteracts octopamine signalling in a neural circuit mediating food response in C. elegans

Suo, Satoshi, Culotti, Joseph G, Van Tol, Hubert H M

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 1.42 MB

english, 2009

28

A hypervariable segment in the human dopamine receptor D4 (DRD4) gene

Lichter, Jay B., Barr, Cathy L., Kennedy, James L., Van Tol, Hubert H.M., Kidd, Kenneth K., Livak, Kenneth J.

Journal:

Human Molecular Genetics

Year:

1993

Language:

english

File:

PDF, 4.70 MB

english, 1993

29

The cloned dopamine D2 receptor reveals different densities for dopamine receptor antagonist ligands. Implications for human brain positron emission tomography

Philip Seeman, Hong-chang Guan, Olivier Civelli, Hubert H.M. Van Tol, Roger K. Sunahara, Hyman B. Niznik

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1992

Language:

english

File:

PDF, 734 KB

english, 1992

30

Functional characterization of the human dopamine D4.2 receptor using vaccinia virus as an expression system

Claudia Bouvier, James R. Bunzow, Hong-Chang Guan, Anja Unteutsch, Olivier Civelli, David K. Grandy, Hubert H.M. Van Tol

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1995

Language:

english

File:

PDF, 637 KB

english, 1995

31

Deriving the therapeutic concentrations for clozapine and haloperidol: The apparent dissociation constant of a neuroleptic at the dopamine D2 or D4 receptor varies with the affinity of the competing radioligand

Philip Seeman, Hubert H.M. Van Tol

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1995

Language:

english

File:

PDF, 724 KB

english, 1995

32

Long-term haloperidol elevates dopamine D4 receptors by 2-fold in rats

Oscar Schoots, Philip Seeman, Hong-Chang Guan, Andrew D. Paterson, Hubert H.M. Van Tol

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1995

Language:

english

File:

PDF, 515 KB

english, 1995

33

The dopamine D4 receptor activates intracellular platelet-derived growth factor receptor β to stimulate ERK1/2

Robin S. Gill, Marilyn S. Hsiung, Chi S. Sum, Natalie Lavine, Stewart D. Clark, Hubert H.M. Van Tol

Journal:

Cellular Signalling

Year:

2010

Language:

english

File:

PDF, 586 KB

english, 2010

34

Dopamine receptors in C. elegans

Satoshi Suo, Shoichi Ishiura, Hubert H.M. Van Tol

Journal:

European Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 170 KB

english, 2004

35

Polymorphisms in dopamine receptors: what do they tell us?

Albert Hung Choy Wong, Chris Eric Buckle, Hubert H.M Van Tol

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 419 KB

english, 2000

36

Nature of the oligomers formed by muscarinic m2 acetylcholine receptors in Sf9 cells

Paul Park, Chi Shing Sum, David R Hampson, Hubert H.M Van Tol, James W Wells

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 500 KB

english, 2001

37

Erratum to “Nature of the oligomers formed by muscarinic m2 acetylcholine receptors in Sf9 cells” [Eur. J. Pharmacol. 421 (2001) 11–22]

Paul Park, Chi Shing Sum, David R. Hampson, Hubert H.M. Van Tol, James W. Wells

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 29 KB

english, 2001

38

Dopamine D2 and D4 receptor ligands: relation to antipsychotic action

Julie M Wilson, Suparna Sanyal, Hubert H.M Van Tol

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 274 KB

english, 1998

39

Review the role of dopamine D4 receptors in schizophrenia and antipsychotic action

Suparna Sanyal, Hubert H.M. Van Tol

Journal:

Journal of Psychiatric Research

Year:

1997

Language:

english

File:

PDF, 945 KB

english, 1997

40

Atypical neuroleptics have low affinity for dopamine D2 receptors or are selective for D4 receptors

Philip Seeman, D. Roy Corbett, Hubert H.M. Van Tol

Journal:

Neuropsychopharmacology

Year:

1997

Language:

english

File:

PDF, 1.97 MB

english, 1997

41

SH3 ligands in the dopamine D3 receptor

John Oldenhof, Andrew Ray, Ross Vickery, Hubert H.M Van Tol

Journal:

Cellular Signalling

Year:

2001

Language:

english

File:

PDF, 278 KB

english, 2001

42

Co-expression of Human Kir3 Subunits Can Yield Channels with Different Functional Properties

Oscar Schoots, Julie M Wilson, Nathalie Ethier, Eve Bigras, Terence E Hebert, Hubert H.M Van Tol

Journal:

Cellular Signalling

Year:

1999

Language:

english

File:

PDF, 577 KB

english, 1999

43

Genomic Organization and Promoter Analysis of the Human G-Protein-Coupled K+Channel Kir3.1 (KCNJ3/HGIRK1)

Oscar Schoots, Theodora Voskoglou, Hubert H.M. Van Tol

Journal:

Year:

1997

Language:

english

File:

PDF, 434 KB

english, 1997

44

In situ hybridization of oxytocin messenger RNA: Macroscopic distribution and quantitation in rat hypothalamic cell groups

J.Peter H. Burbach, Theodora A.M. Voorhuis, Hubert H.M. van Tol, Richard Ivell

Journal:

Biochemical and Biophysical Research Communications

Year:

1987

Language:

english

File:

PDF, 561 KB

english, 1987

45

Immunological studies with a monoclonal antibody suggest a different conformation of neurophysin in parvicellular neurons of rat hypothalamus

Gajanan Nilaver, Lawrence C. Rosenbaum, Hubert H.M. Van Tol, Eva Marie Shannon, Heidi M. Hagman, Earl A. Zimmerman, Edward A. Neuwelt

Journal:

Year:

1990

Language:

english

File:

PDF, 937 KB

english, 1990

46

Dopamine D4 receptors bind inactive (+)-aporphines, suggesting neuroleptic role. Sulpiride not stereoselective

Philip Seeman, Hubert H.M. Van Tol

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 190 KB

english, 1993

47

Schizophrenia: elevation of dopamine D4-like sites, using [3H]nemonapride and [125I]epidepride

Philip Seeman, Hong-Chang Guan, Hubert H.M. Van Tol

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 199 KB

english, 1995

48

A human somatostatin receptor (SSTR3), located on chromosome 22, displays preferential affinity for somatostatin-14 like peptides

Jacquie D. Corness, Lidia L. Demchyshyn, Philip Seeman, Hubert H.M. Van Tol, Coimbatore B. Srikant, Gillian Kent, Yogesh C. Patel, Hyman B. Niznik

Journal:

Year:

1993

Language:

english

File:

PDF, 784 KB

english, 1993

49

Characterization of the desensitization properties of five dopamine receptor subtypes and alternatively spliced variants of dopamine D2 and D4 receptors

Dong-Im Cho, SunRyeo Beom, Hubert H.M.Van Tol, Marc G. Caron, Kyeong-Man Kim

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 398 KB

english, 2006

50

Influence of the antipsychotic drug pipamperone on the expression of the dopamine D4 receptor

Kathleen Van Craenenbroeck, Evelien Gellynck, Béatrice Lintermans, Josée E. Leysen, Hubert H.M. Van Tol, Guy Haegeman, Peter Vanhoenacker

Journal:

Year:

2006

Language:

english

File:

PDF, 1.01 MB

english, 2006